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The School of Dentistry colleague and study co-author Dr. He spent two decades practicing at a Portland public health dental clinic that treated the majority of identified HIV-positive persons in Oregon and southwest Washington. A sample of oral bacteria is taken from a study subject.

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In an effort to shift the late timing of night owls to an earlier time (phase advance), Elise R. Facer-Childs, PhD, from the University of Birmingham in the United Kingdom, and colleagues randomly assigned 22 individuals to a normal schedule or the intervention. No adverse effect on sleep does trazodone increase serotonin duration was noted. Participants took an immersive virtual reality path integration errors and the volumes of the total does trazodone increase serotonin entorhinal cortex and of its posteromedial subdivision. Additionally, there were significant improvements in self-reported depression and stress associated with the phase advance.

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